Shuri uni has the most staying power here. It gives CTPR at mythic if you’rve got the BP extreme pack; it also makes her better at support which will still be useful when the HB and Spidy IW unis fall out of style. Spidey is also great for Timeline.
Spidey IW uni helps for PVP battle and lower stages of proxima.
If you are having problem in those modes, then go for the uni.
Shuri uni gives extra support boost amd makes her better.
HB uni makes him a beast.